A new research study has found that fat contained specifically within the pancreas is associated with type 2 diabetes, and that losing this fat can reverse the condition.
A recent study published in the journal Diabetes Care has reported the results of a clinical trial that investigated the role of weight loss in type 2 diabetes. Specifically, the study assessed reductions in fat located within the pancreas.
Patients undergoing gastric bypass surgery were included in the study. They were assessed prior to surgery and after surgery for levels of fat in their liver and insulin sensitivity. These measurements revealed that, prior to surgery, patients who had type 2 diabetes had a higher level of fat in their pancreas than patients who did not have type 2 diabetes.
Following surgery, both patients with and without diabetes lost the same amount of weight, approximately 13% of their initial body weight. However, the researchers found that in patients with type 2 diabetes who lost weight following gastric bypass surgery had a reduction in the levels of fat in their pancreas, whereas there was no reduction of pancreatic fat seen in patients who did not have type 2 diabetes.
The study revealed that fat contained in the pancreas is specifically related to type 2 diabetes, and when that fat is lost, the levels of insulin return to normal, and patients are no longer diabetic.
Steven, S, Hollingsworth, KG, Small, PK, Woodcock, SA, Pucci, A, Aribisala, B, Al-Mrabeh, A, Daly, AK, Batterham, RL, Taylor, R. “Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes” Diabetes Care December 1, 2015
Written by Deborah Tallarigo, PhD